We know a lot about what can go wrong inside cells during disease. But what about the healthy bystanders?
Your body is a mosaic of cells, all squished together to form the tissues and organs that allow you to digest, think and breathe. The proper function of these organs depends entirely on the health and behavior of the individual cells that make them up, and disease occurs when cells don’t behave normally. For example, cancer is caused by cells that divide over and over again when they should not. But what happens to the innocent bystanders, the well-behaved cells next door to the troublemakers, during disease?
Continue reading “The cancer cell next door”
Scientists at Yale use gene-editing technology to understand the remarkable regenerative abilities of an adorable amphibian.
In 1864, a small shipment arrived in Paris from French colonialists in Mexico. It consisted of six fairly unremarkable animals — three female deer and three small dogs — and thirty-four monumentally strange animals that were like nothing to have set foot in France before. These aquatic organisms had buggy eyes and bizarre, lacy gills, and carried with them a strange name from the New World: axolotl.
Continue reading “A cutting-edge tool reveals the secrets of a salamander with superpowers”
You are roughly half bacteria. In terms of cell number, that is. It’s a disorienting reality to swallow, but the body that allows you to dance and digest is utterly dependent on the work of millions of bacterial collaborators. They colonize your gut, pulling off complicated chemical reactions to produce nutrients necessary for your survival (biotin and vitamin K, to name a few). They patrol your skin, forming complex communities that ward off dangerous disease-causing interlopers. And, research published last week shows that they may also affect brain development and the efficacy of cancer drugs. Continue reading “The Frenemy Inside You: tales of bacterial cooperation and collusion”